![]() As expected, effectiveness as measured by faster aspiration of secretions also was directly related to vacuum pressure ( P =. The time to aspirate mucus simulant was significantly different from ISIS vs Evac ( P =. ![]() The mean time it took to aspirate 5 mL or 10 mL of 0.5% mucus simulant from the ISIS, Evac, and SACETT ETTs at continuous pressure is shown in Figure 3 and Table 3. 8 Two concentrations of mucus simulant were used (0.5% and 1.5%) with rheologic properties similar to saliva and mucus, Continuous Suction Pressure and 0.5% Mucus Simulant 7 We used this simulant in earlier studies of suction catheter design and performance. This polymer simulant is homogenous and has viscoelastic properties similar to human airway mucus (Table 1). We found large differences in suction tubing cross-sectional area between the ISIS and the other tubes, and flow calculations using the Hagen-Poiseuille equation can explain the observed differences in volumes aspirated and tendency toward lumen obstruction.Ī mucus simulant was prepared daily using Polyox Water-Soluble Resin N-750 NF (Dow Chemicals Woodbury, NJ), a polyethylene oxide with an approximate molecular weight of 5 × 10 6. The ISIS was more prone to obstruction by the flexible membrane than the Evac. In a trachea model with a flexible posterior membrane, this membrane either partially or completely occluded the suction port of all tubes at high continuous or intermittent suction. For low and continuous suction, suction ports in all ETTs occluded with mucus, except for ISIS, at the highest continuous suction tested. 0001) the Evac was more effective than the SACETT ( P =. ![]() For mucus simulant, the ISIS aspirated stimulant better than the other ETTs at high intermittent suction ( P <. 0001) as well as with intermittent high pressure suction ( P <. In a rigid tracheal model, the ISIS aspirated saliva simulant more quickly with continuous low pressure suction than Evac ( P =. ![]()
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